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Effects of passive smoking and breastfeeding on childhood bronchial asthma
E M Wafula1, M S Limbe, F E Onyango
1Department of Paediatrics and Child Health, Aga Khan Hospital, Nairobi.
Insights
Passive smoking increases the risk of early-onset asthma and potentially severe asthma. Exclusive breastfeeding protects against severe asthma but does not influence the age of onset.
Area of Science:
- Pediatrics
- Environmental Health
- Respiratory Medicine
Background:
- Asthma is a significant pediatric respiratory condition.
- Early life exposures like passive smoking and breastfeeding patterns may influence asthma development and severity.
Purpose of the Study:
- To investigate the impact of passive smoking and breastfeeding on the onset age and severity of bronchial asthma in children.
Main Methods:
- A cross-sectional study was conducted.
- Participants included children aged 1-120 months at Kenyatta National Hospital.
- Data on passive smoking exposure and breastfeeding practices were collected.
Main Results:
- Passive smoking was significantly associated with earlier onset of wheezing (Odds ratio = 2.44, p = 0.012).
- Exclusive breastfeeding showed a significant protective effect against severe bronchial asthma (Odds ratio = 0.4, p = 0.045).
- Passive smoking showed a non-significant trend towards increased asthma severity, while breastfeeding did not affect the age of onset.
Conclusions:
- Passive smoking is linked to early-onset asthma and potentially severe disease.
- Exclusive breastfeeding offers protection against severe asthma.
- Breastfeeding duration does not appear to influence the age of asthma onset.
Objective:
To evaluate the effect of passive smoking and breastfeeding on the severity and age of onset of bronchial asthma.
Design:
Cross-sectional study.
Setting:
Paediatric observation ward and paediatric chest clinic, Kenyatta National Hospital.
Patients:
Children aged between one and 120 months.
Results:
More than fifty per cent of the children had their first wheeze at less than 12 months of age and 68% were categorised as having moderate to severe asthma. Passive smoking was positively significantly associated with early onset of wheezing (chi 2 = 6.22, p = 0.012, Odds ratio = 2.44, 95% CI 1.2,5.0), and also, at a non significant level, to severity of asthma (chi 2 = 2.8, p = 0.09, Odds ratio = 2.1, 95% CI 0.9,4.7). On the other hand, exclusive breastfeeding was significantly negatively associated with severity of bronchial asthma (chi 2 = 4.02, p = 0.045, Odds ratio = 0.4, 95% CI 0.14,0.98), but did not seen to have effect on age of onset of the disease (chi 2 = 0.0006, p = 0.94, Odds ratio = 0.9, 95% CI 0.4,2.2).
Conclusion:
Passive smoking is associated with early onset of asthma and possibly with development of severe asthma while exclusive breastfeeding is protective against development of severe asthma but does not seem to affect the age of onset of this disease.
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