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Related Experiment Videos

Viral folliculitis on the face.

K A Jang1, S H Kim, J H Choi

  • 1Department of Dermatology, Asan Medical Center, College of Medicine, University of Ulsan, 388-1 Poongnap-Dong, Songpa-Gu, Seoul 138-736, Korea.

The British Journal of Dermatology
|March 29, 2000
PubMed
Summary

Herpes simplex virus (HSV) and molluscum contagiosum (MC) can cause folliculitis, a rare condition potentially indicating immunosuppression. Prompt diagnosis and treatment are crucial for resolution without scarring.

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Area of Science:

  • Dermatology
  • Virology
  • Pathology

Background:

  • Herpes simplex virus (HSV) and molluscum contagiosum (MC) commonly present with distinct lesions, but can manifest as folliculitis.
  • Viral folliculitis is infrequently reported and may suggest underlying immunosuppression, including human immunodeficiency virus (HIV) infection.

Purpose of the Study:

  • To characterize the clinical and histopathological features of viral folliculitis caused by HSV and MC.
  • To identify potential associations with immunosuppression and evaluate treatment outcomes.

Main Methods:

  • Retrospective analysis of seven patients with histologically confirmed HSV or MC folliculitis (1994-1999).
  • Review of clinical presentations, histopathology, immunosuppression workup, and treatment responses.

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Main Results:

  • Patients presented with folliculitis refractory to initial treatments; diagnoses included bacterial folliculitis or inflammatory conditions.
  • Histopathology revealed molluscum bodies or herpetic changes within follicular epithelium.
  • Three patients had evidence of immunosuppression (pregnancy, hepatitis B, nasopharyngeal carcinoma); HIV tests were negative.

Conclusions:

  • Molluscum folliculitis treated with curettage resolved without recurrence or scarring.
  • Herpetic folliculitis responded to antihistamines or acyclovir.
  • Consider MC or HSV in refractory folliculitis-like dermatoses, especially in potentially immunocompromised individuals.