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Serovars of Mycobacterium avium complex isolated from AIDS and non-AIDS patients in Spain
J B Torrelles1, D Chatterjee, J G Lonca
1Servei de Microbiología, Hospital Universitari Germans Trias i Pujol de Badalona, Facultat de Medicina de la Universitat Autònoma de Barcelona, Spain. jtorrell@cvmbs.colostate.edu
Abstract:
Antigen fingerprinting based on surface glycolipid antigens was applied to the epidemiology of clinical isolates of the Mycobacterium avium complex from 128 acquired immunodeficiency syndrome (AIDS) and 31 non-AIDS patients from several different regions of Spain. The application of thin-layer chromatography, gas chromatography-mass spectrometry and monoclonal antibodies, combined with ELISA, allowed a facile identification, differentiation and classification of the isolates. The cumulative results demonstrate that, among the clinical isolates, serovar 4 was predominant in both AIDS (33.6%) and non-AIDS (22.6%) isolates. In general, the results demonstrate geographical as well as disease-related differences in the distribution of Myco. avium complex serovars of clinical importance.