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Updated: Oct 8, 2026

A Macrophage Reporter Cell Assay to Examine Toll-Like Receptor-Mediated NF-kB/AP-1 Signaling on Adsorbed Protein Layers on Polymeric Surfaces
Published on: January 7, 2020
[Macrophage receptors]
1Katedra Immunologii Instytutu Mikrobiologii i Immunologii, Uniwersytetu Lódzkiego.
Abstract:
Macrophages play a very important role in specific and nonspecific immune response. They are involved in different processes such as phagocytosis and killing of microorganisms, antigen presentation and production of cytokines etc. Their biological activity, ability to cooperate with other cells and to receive signals from extracellular environment are determined by their surface membrane receptors. The paper describes the structure and role of Fc receptors (FcR), adhesion receptors, complement receptors (CR), CD14 (LPS receptors) and receptors for chemotactic agents, present on the surface of macrophages.
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