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Three-channeled aortic dissection in Marfan syndrome
1Department of Cardiovascular Surgery, National Cardiovascular Center, Suita, Osaka, Japan.
Cardiovascular Surgery (London, England)
|March 29, 2000
Summary
Three-channeled aortic dissection, a rare condition with two false lumens, is notably frequent in Marfan syndrome patients. Prompt surgical intervention is crucial for these patients, especially when pain recurs.
Area of Science:
- Cardiovascular Surgery
- Genetics
- Radiology
Background:
- Three-channeled aortic dissection, characterized by two adjacent false lumens, is a rare but significant complication.
- Marfan syndrome is associated with a high incidence of aortic dissection, including this complex variant.
Purpose of the Study:
- To analyze the surgical treatment and outcomes of Marfan syndrome patients with three-channeled aortic dissection.
- To highlight the importance of suspecting this condition in Marfan patients experiencing recurrent pain.
Main Methods:
- Retrospective analysis of 20 Marfan syndrome patients surgically treated for three-channeled aortic dissection before July 1999.
- Preoperative diagnosis utilized computed tomography (CT) and magnetic resonance imaging (MRI).
- Surgical procedures included descending aorta replacement, thoracoabdominal aortic replacement, and bypass grafting.
Main Results:
- The 20 patients represented 29.4% of all Marfan aortic dissection cases treated at the institution.
- Pain was a presenting symptom in 13 patients.
- Hospital mortality was 20% (4 patients), with three late deaths during a mean follow-up of 51 months.
Conclusions:
- Three-channeled aortic dissection occurs with high frequency in Marfan syndrome.
- Recurrent pain in Marfan patients with aortic dissection warrants suspicion of this specific morphology.
- Timely surgical management is essential for improving outcomes in these complex cases.
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