[Clinical manifestations and possible causes of dystrophic changes in corneal flap after laser specialized...

Main types of dystrophic complications on the corneal flap associated with laser specialized keratomileusis (LASIK) are discussed. A total of 6507 down-up LASIK operations were performed. The most grave form of corneal flap disadaptation syndrome (CFDS) (central dystrophy) occurred in 1.59% cases only in patients with myopic keratoablation. Slight manifestations of this syndrome were observed in patients with myopia and hypermetropia. The authors discuss a concept of CFDS development in which the leading role is attributed to the initial disagreement between the size of corneal flap before and after keratoablation. The incidence of such complications depends on the method of corneal flap positioning during the final phase of the operation. Clinical picture, outcome, and treatment of CFDS are discussed.