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Symptoms associated with infant teething: a prospective study.

M L Macknin1, M Piedmonte, J Jacobs

  • 1Departments of Pediatrics and Adolescent Medicine, Cleveland Clinic Foundation, Cleveland, OH 44195, USA. macknin@ccf.org

Pediatrics
|April 1, 2000
PubMed
Summary

This large prospective study found that while some mild symptoms like irritability and mild temperature elevation are linked to infant teething, they cannot reliably predict tooth emergence. Always rule out serious illnesses before attributing symptoms to teething.

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Area of Science:

  • Pediatric Health
  • Infant Development
  • Dental Health

Background:

  • Previous infant teething studies were limited by small sample sizes, retrospective designs, or institutionalized populations.
  • A need existed for a large, prospective investigation into teething symptoms in healthy infants.

Purpose of the Study:

  • To identify symptoms reliably attributable to infant teething.
  • To determine if specific symptoms can predict tooth emergence in infants.

Main Methods:

  • A prospective cohort study involving 125 healthy infants from a clinic-based pediatric practice.
  • Parents meticulously recorded daily temperatures, 18 symptoms, and tooth eruptions for one year.
  • Data analysis focused on a defined 8-day teething period around tooth emergence.

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Main Results:

  • Symptoms significantly associated with teething included increased biting, drooling, irritability, mild temperature elevation, and facial rash.
  • Symptoms like fever over 102°F, vomiting, and congestion were not significantly linked to tooth emergence.
  • No single symptom reliably predicted tooth emergence, and no severe illnesses were associated with teething.

Conclusions:

  • Mild symptoms are temporally associated with infant teething but do not reliably predict tooth eruption.
  • Caregivers must consider and rule out other potential causes for infant symptoms before concluding they are due to teething.
  • This research clarifies the symptom profile of teething and emphasizes the importance of differential diagnosis for infant illness.