Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Cerebral malaria in children].

J J García-Peñas1, V Quintero, L G Gutiérrez-Solana

  • 1Sección de Neurología-2, Hospital Niño Jesús, Madrid, España.

Revista De Neurologia
|April 1, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prevalence of orthopaedic conditions in Rett syndrome: a systematic review and meta-analysis.

Journal of intellectual disability research : JIDR·2024
Same author

Cerebral and cerebellar pseudoatrophy associated with valproic acid. Report of three pediatric cases.

Revista de neurologia·2023
Same author

[The electroencephalogram: a complementary test that should not be forgotten to perform before a first seizure. Reply].

Revista de neurologia·2023
Same author

[Paediatric status epilepticus].

Revista de neurologia·2022
Same author

[Variability of the clinical expression of KCNB1 encephalopathy].

Revista de neurologia·2021
Same author

Cannabidiol for the treatment of Lennox-Gastaut syndrome and Dravet syndrome: experts' recommendations for its use in clinical practice in Spain.

Revista de neurologia·2021

Cerebral malaria, a severe complication of Plasmodium falciparum infection, presents with neurological symptoms and can lead to long-term disability. Increased awareness is crucial for timely diagnosis and treatment of imported malaria cases.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Pediatrics

Background:

  • Malaria, caused by Plasmodium falciparum, is a major global health issue, particularly in developing countries.
  • Cerebral malaria is a life-threatening complication in children, characterized by altered consciousness, P. falciparum parasitemia, and acute encephalopathy.
  • High mortality rates (up to 50%) and significant long-term neurological deficits (around 20%) underscore the severity of cerebral malaria.

Observation:

  • This study reviewed three pediatric cases of cerebral malaria diagnosed between 1990 and 1998 in Spain.
  • All patients exhibited acute encephalopathy, presenting with fever, obtundation, and seizures.
  • Neurological sequelae, primarily hemiparesis, were observed in all affected children.

Findings:

Related Experiment Videos

  • The reviewed cases highlight the occurrence of cerebral malaria in non-endemic regions.
  • Neurological manifestations, including encephalopathy and seizures, are key indicators of severe malaria.
  • Residual neurological deficits are a common outcome in survivors of pediatric cerebral malaria.

    • Implications:

    • Increased global travel and migration necessitate greater awareness of imported malaria among healthcare professionals, especially pediatricians.
    • Prompt diagnosis and appropriate treatment, potentially with parenteral quinine due to resistant strains, are critical for improving outcomes.
    • Further research and education are needed to manage the rising incidence of imported malaria and its neurological complications.