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[Influence of intercellular adhesion molecule-1 transcription on nasal epithelial cell by airborne allergenic
Abstract:
Eleven patients with Artemisia allergic rhinitis were evaluated. Among them 8 were studied during pollen season and 3 out of pollen season. Intercellular adhesion molecule-1(ICAM-1) was detected on nasal epithelial cells by reverse transcription polymerase chain reaction (RT-PCR). The results showed that ICAM-1 was detectable from all samples in the pollen season. However, during off-pollen season 2 of the 3 samples were negative, 1 was positive (who was also positive to house dust). It is suggested that ICAM-1 is detectable on nasal epithelial cells during exposure to specific allergen.