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Laparoscopic and open live donor nephrectomy: a cost/benefit study.

T Berney¹, J Malaise, M Mourad

¹Kidney and Pancreas Transplantation Unit, University of Louvain Medical School, Brussels, Belgium.

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|April 1, 2000

Summary

Laparoscopic live-donor nephrectomy significantly reduces postoperative pain compared to open surgery. This safe procedure is not detrimental to allograft kidney function, offering potential cost savings.

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Area of Science:

Nephrology
Minimally Invasive Surgery
Organ Donation

Background:

Laparoscopic live-donor nephrectomy (LSC) has emerged to enhance organ availability.
Minimally invasive techniques aim to improve donor outcomes.

Purpose of the Study:

To compare the outcomes of laparoscopic transperitoneal versus open extraperitoneal live-donor nephrectomy.
To evaluate postoperative pain, morbidity, allograft function, and cost-effectiveness.

Main Methods:

Retrospective review of 10 donors undergoing open extraperitoneal nephrectomy.
Comparison with 10 donors undergoing laparoscopic transperitoneal nephrectomy (LSC).

Main Results:

LSC group showed significantly reduced postoperative narcotic use (109 mg vs 272 mg; P < 0.0005).

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Morbidity and postoperative stay were similar between groups.

Allograft kidney function remained comparable up to 6 months post-donation.

Conclusions:

Laparoscopic live-donor nephrectomy is a safe procedure with reduced postoperative pain.
It does not negatively impact allograft kidney function.
Cost-effectiveness is achieved if postoperative stay is reduced by 3 days, despite higher disposable material costs.