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Published on: September 21, 2018
Heart rate recovery after submaximal exercise testing as a predictor of mortality in a cardiovascularly healthy
C R Cole1, J M Foody, E H Blackstone
1Department of Cardiology, Cleveland Clinic Foundation, Ohio 44195, USA.
Background:
Abnormal heart rate recovery after symptom-limited exercise predicts death. It is unknown whether this is also true among patients undergoing submaximal testing.
Objective:
To test the prognostic implications of heart rate recovery in cardiovascularly healthy adults undergoing submaximal exercise testing.
Design:
Population-based cohort study.
Setting:
10 primary care sites.
Participants:
5234 adults without evidence of cardiovascular disease who were enrolled in the Lipid Research Clinics Prevalence Study.
Measurements:
Heart rate recovery was defined as the change from peak heart rate to that measured 2 minutes later (heart rate recovery was defined as < or =42 beats/min).
Results:
During 12 years of follow-up, 312 participants died. Abnormal heart rate recovery predicted death (relative risk, 2.58 [CI, 2.06 to 3.20]). After adjustment for standard risk factors, fitness, and resting and exercise heart rates, abnormal heart rate recovery remained predictive (adjusted relative risk, 1.55 [CI, 1.22 to 1.98]) (P<0.001).
Conclusion:
Even after submaximal exercise, abnormal heart rate recovery predicts death.
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