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Updated: Aug 17, 2026

Sub-acute Cerebral Microhemorrhages Induced by Lipopolysaccharide Injection in Rats
Published on: October 17, 2018
Salmonella endocarditis presenting as cerebral hemorrhage
1Department of Internal Medicine, Clínica Puerta de Hierro, San Martín de Porres, 4, 28035, Madrid, Spain
Abstract:
The case of a 35-year-old male with cerebral hemorrhage as a presenting complication of infective endocarditis of the aortic valve, caused by Salmonella typhimurium, is described. We emphasize the infrequent etiology and review the mechanisms of intracranial hemorrhage in infective endocarditis.
Insights
A rare case of Salmonella typhimurium infective endocarditis caused aortic valve cerebral hemorrhage in a 35-year-old male. This study highlights the uncommon causes and mechanisms of intracranial bleeding in infective endocarditis.
Area of Science:
- Neurology
- Infectious Diseases
- Cardiology
Background:
- Infective endocarditis (IE) is a serious infection affecting heart valves.
- Intracranial hemorrhage (ICH) is a rare but severe complication of IE.
- Salmonella typhimurium is an uncommon pathogen in IE.
Purpose of the Study:
- To describe a unique case of cerebral hemorrhage secondary to Salmonella typhimurium infective endocarditis.
- To review the known mechanisms linking IE to ICH.
Main Methods:
- Case report presentation.
- Literature review of IE and ICH.
Main Results:
- A 35-year-old male presented with cerebral hemorrhage due to Salmonella typhimurium aortic valve endocarditis.
- IE is an infrequent cause of ICH.
Conclusions:
- Salmonella typhimurium can cause infective endocarditis leading to severe neurological complications like cerebral hemorrhage.
- Understanding the mechanisms of ICH in IE is crucial for timely diagnosis and management.
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