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Updated: Oct 17, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Intra-arterial reteplase for the treatment of acute limb ischemia
1Cardiovascular Research Foundation, 110 Irving Street N.W., Suite 4B-1, Washington, D.C. 20010, USA. jrl2@mhg.edu
Abstract:
The removal of urokinase from the market has created a dilemma for interventionists and vascular surgeons treating patients with acute limb threatening ischemia due to arterial thrombosis or embolization. Reteplase is a newer, fibrin-specific thrombolytic agent with properties that make it an attractive alternative to urokinase. We report two cases of successful treatment of acute, limb threatening ischemia with intra-arterial Reteplase therapy.
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