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Updated: Jul 31, 2026

A Protocol for Computer-Based Protein Structure and Function Prediction
Published on: November 3, 2011
Sausage: protein threading with flexible force fields
T Huber1, A J Russell, D Ayers
1Research School of Chemistry, Australian National University, Canberra, Australia.
Abstract:
Sausage is a protein sequence threading program, but with remarkable run-time flexibility. Using different scripts, it can calculate protein sequence-structure alignments, search structure libraries, swap force fields, create models from alignments, convert file formats and analyse results. There are several different force fields which might be classed as knowledge-based, although they do not rely on Boltzmann statistics. Different force fields are used for alignment calculations and subsequent ranking of calculated models.
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