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[Focal echogenic splenic involvement in malignant lymphoma: a diagnostic problem]
J Riera-Knorrenschild1, C Görg, N Dennhardt
1Medizinische Universitätsklinik, Marburg.
Ultraschall in Der Medizin (Stuttgart, Germany : 1980)
|April 4, 2000
Summary
Echorich splenic lymphoma involvement is a rare finding in patients with malignant lymphoma, often presenting as small lesions in enlarged spleens. Its clinical significance and variable sonographic presentation require further investigation.
Area of Science:
- Radiology
- Oncology
- Pathology
Background:
- Malignant lymphoma can involve the spleen, presenting with diverse sonographic findings.
- Focal splenic lesions are a known manifestation, but echorich patterns are infrequently reported.
Purpose of the Study:
- To characterize the clinical data, frequency, sonographic patterns, and diagnostic confirmation of focal echorich splenic lymphoma involvement.
- To differentiate echorich splenic lesions from other splenic pathologies.
Main Methods:
- Retrospective analysis of 178 patients with malignant lymphoma over 20 years.
- Identification and detailed sonographic evaluation of 11 cases with echorich splenic lesions.
- Correlation of sonographic findings with clinical data, follow-up, and autopsy where available.
Main Results:
- Echorich splenic lesions were identified in 6.2% (11/178) of patients with malignant lymphoma.
- These lesions predominantly occurred in low-grade Non-Hodgkin-Lymphoma (9/11 cases).
- Lesions were typically <3 cm in diameter within enlarged spleens (>8x20 cm in 9/11 cases).
Conclusions:
- Echorich splenic lymphoma involvement is a rare sonographic finding.
- It exhibits a variable presentation during ultrasound follow-up.
- The clinical significance of this rare finding remains to be elucidated.