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Chronic idiopathic intestinal pseudo-obstruction.

J C Yan1, Y C Chao, W G Chang

  • 1Department of Internal Medicine, China Medical Center Hospital, Taichung, ROC.

Zhonghua Yi Xue Za Zhi = Chinese Medical Journal; Free China Ed
|April 4, 2000
PubMed
Summary

Chronic idiopathic intestinal pseudo-obstruction (CIIP) is a rare condition causing bowel obstruction symptoms without a blockage. This report details two CIIP cases, highlighting severe gastrointestinal and urinary tract involvement, with one patient succumbing to complications.

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Area of Science:

  • Gastroenterology
  • Nephrology
  • Neurology

Background:

  • Chronic idiopathic intestinal pseudo-obstruction (CIIP) is a rare, heterogeneous syndrome mimicking mechanical bowel obstruction.
  • It is characterized by recurrent symptoms of intestinal obstruction without an identifiable mechanical lesion.
  • Visceral dilatation, including urinary tract structures, occurs in a minority of CIIP patients.

Observation:

  • Two CIIP cases presented with abdominal fullness and constipation.
  • Case 1 showed extensive gastrointestinal dilatation and peripheral polyneuropathy with poor bladder sensation.
  • Case 2 exhibited gastric and intestinal distention with bilateral hydronephrosis, linked to minimal change disease.

Findings:

  • CIIP can manifest with severe gastrointestinal dysmotility and significant urinary tract dilation.

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  • Neuropathy and impaired bladder sensation were noted in one patient, indicating systemic involvement.
  • Minimal change disease contributed to proteinuria and hydronephrosis in the second patient.

    • Implications:

    • These cases underscore the complex, multisystemic nature of CIIP.
    • Early recognition and comprehensive management are crucial for improving outcomes in CIIP patients.
    • Further research into CIIP's pathophysiology and treatment strategies is warranted.