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Does severe nutcracker phenomenon cause pediatric chronic fatigue?

Y Takahashi1, S Ohta, A Sano

  • 1Department of Pediatrics, Tenri Hospital, Nara, Japan.

Clinical Nephrology
|April 5, 2000
PubMed

Insights

Nine children with chronic fatigue syndrome (CFS/CF) were found to have severe nutcracker phenomenon (NC). This condition was associated with autonomic dysfunction symptoms, suggesting a potential link in pediatric cases.

Area of Science:

  • Pediatric Medicine
  • Cardiology
  • Nephrology

Background:

  • Nine children with chronic fatigue were evaluated over five years.
  • These children experienced intermittent or persistent school absenteeism.
  • Initial suspicions included psychosomatic disorders and autonomic dysfunction.

Purpose of the Study:

  • To investigate the underlying causes of chronic fatigue in children.
  • To explore potential associations between physical conditions and chronic fatigue syndrome/idiopathic chronic fatigue (CFS/CF).

Main Methods:

  • Children presenting with chronic fatigue and suspected autonomic dysfunction were assessed.
  • Diagnostic investigations included evaluation for orthostatic proteinuria.
  • Accidental discovery of severe nutcracker phenomenon (NC) during the diagnostic process.

Main Results:

  • All nine children with chronic fatigue exhibited severe typical nutcracker phenomenon (NC).
  • Orthostatic proteinuria was noted in some of the children.
  • The children's symptoms met the diagnostic criteria for chronic fatigue syndrome or idiopathic chronic fatigue (CFS/CF).

Conclusions:

  • A significant association exists between severe nutcracker phenomenon (NC) and autonomic dysfunction symptoms in children diagnosed with CFS/CF.
  • Nutcracker phenomenon may be an underrecognized contributor to chronic fatigue and associated symptoms in pediatric populations.
Abstract

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