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Salmonella infection of a ventricular aneurysm with mural thrombus

Y Zheng1, M K Rai, K A Adal

  • 1Department of Infectious Disease, The Cleveland Clinic Foundation, Ohio 44195, USA.

The Annals of Thoracic Surgery
|April 6, 2000
PubMed

Insights

Salmonella infection can affect left ventricular aneurysms with thrombi. Early diagnosis and aggressive treatment combining medical and surgical approaches are crucial for survival in these rare cardiac cases.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Medical Imaging

Background:

  • Salmonella bacteremia can lead to rare but severe cardiac complications.
  • Infection of a left ventricular aneurysm (LVA) with a mural thrombus is a critical condition.

Observation:

  • A case of Salmonella infection of an LVA with mural thrombus is presented.
  • A review of 12 similar cases from the literature is included.
  • Persistent or relapsing Salmonella bacteremia with an intracardiac thrombus raises suspicion for this entity.

Findings:

  • Nuclear imaging may aid in the diagnosis of infected LVAs.
  • Aggressive combined medical and surgical management is recommended.
  • Patients not undergoing aneurysmectomy have a poor prognosis.

Implications:

  • This condition requires high clinical suspicion in patients with recurrent Salmonella bacteremia and cardiac thrombi.
  • Prompt diagnosis and intervention, including aneurysmectomy, are vital for improving patient survival.
  • Further research into the optimal management strategies for infected LVAs is warranted.

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