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Updated: Aug 3, 2026

Performing and Processing FNA of Anterior Fat Pad for Amyloid
Published on: October 30, 2010
Mediastinal amyloidosis
1Department of Thoracic Surgical Oncology, Roswell Park Cancer Institute, Buffalo, New York, USA. urschelj@fhs.mcmaster.ca
Abstract:
Systemic amyloidosis is an unusual cause of mediastinal lymphadenopathy. Thoracic surgeons are often called upon to establish a diagnosis in patients with mediastinal lymphadenopathy, so familiarity with mediastinal amyloidosis is valuable. We report our experience with 2 patients, and discuss the diagnostic role of mediastinoscopy and other less invasive biopsy techniques. General anesthesia may pose significant risks in this disease; nonoperative biopsy techniques should be considered if the diagnosis of amyloidosis is suspected.
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