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Treatment of multifocal motor neuropathy with interferon-beta1A
R M Van den Berg-Vos1, L H Van den Berg, H Franssen
1Departments of Neurology, Rudolf Magnus Institute for Neurosciences, University Medical Center Utrecht, the Netherlands.
Neurology
|April 6, 2000
Abstract:
Nine patients with multifocal motor neuropathy who had previously responded favorably to IV immunoglobulins (IVIg) were treated with interferon-beta1a. Muscle strength and disability were evaluated. In six patients there was no effect of treatment. Four patients deteriorated in such a way that IVIg had to be restarted during the study. Three patients showed an improvement that was more pronounced than on IVIg. These patients had a shorter disease duration and were less affected clinically and electrophysiologically than those who did not respond.