Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Boracic Acid in the Treatment of Leucorrhœa.

Buffalo medical and surgical journal·2023
Same author

A retrospective analysis of palliative colonic stent placement in an elderly population.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland·2013
Same author

Streptomycin in influenzal meningitis.

Case reports. Children's Memorial Hospital (Chicago, Ill.)·2010
Same author

Lupus erythematosus.

Archives of pediatrics·2010
Same author

Weakness and fever [amyotonia congenita].

Case reports. Children's Memorial Hospital (Chicago, Ill.)·2010
Same author

Loss of ability to speak, walk, and sit up.

Case reports. Children's Memorial Hospital (Chicago, Ill.)·2010

Related Experiment Video

Updated: Jul 15, 2026

A Novel Approach to Monitoring Graft Neovascularization in the Human Gingiva
07:51

A Novel Approach to Monitoring Graft Neovascularization in the Human Gingiva

Published on: January 12, 2019

Interobserver Reproducibility and Biological Variability of the Surgicutt II Bleeding Time.

Schwartz1, Brister, Bourassa

  • 1University of Toronto and The Toronto Hospital, Toronto, Ontario, Canada.

Journal of Thrombosis and Thrombolysis
|February 7, 2001
PubMed
Summary

The bleeding time test shows wide individual variation but little biological variability within a person. Most differences over time are due to interobserver variability, suggesting its clinical utility for monitoring platelet responsiveness.

More Related Videos

Doppler Ultrasound-Based Leg Blood Flow Assessment During Single-Leg Knee-Extensor Exercise in an Uncontrolled Setting
09:18

Doppler Ultrasound-Based Leg Blood Flow Assessment During Single-Leg Knee-Extensor Exercise in an Uncontrolled Setting

Published on: December 15, 2023

Cortical Bone Assessment Using Ultrasonic Guided Waves: A Reproducibility Study in a Healthy Population
09:02

Cortical Bone Assessment Using Ultrasonic Guided Waves: A Reproducibility Study in a Healthy Population

Published on: January 31, 2025

Related Experiment Videos

Last Updated: Jul 15, 2026

A Novel Approach to Monitoring Graft Neovascularization in the Human Gingiva
07:51

A Novel Approach to Monitoring Graft Neovascularization in the Human Gingiva

Published on: January 12, 2019

Doppler Ultrasound-Based Leg Blood Flow Assessment During Single-Leg Knee-Extensor Exercise in an Uncontrolled Setting
09:18

Doppler Ultrasound-Based Leg Blood Flow Assessment During Single-Leg Knee-Extensor Exercise in an Uncontrolled Setting

Published on: December 15, 2023

Cortical Bone Assessment Using Ultrasonic Guided Waves: A Reproducibility Study in a Healthy Population
09:02

Cortical Bone Assessment Using Ultrasonic Guided Waves: A Reproducibility Study in a Healthy Population

Published on: January 31, 2025

Area of Science:

  • Clinical pathology
  • Hematology

Background:

  • The bleeding time (BT) is a common clinical test for assessing hemostasis.
  • Its performance and interpretation involve subjectivity, impacting reliability.

Purpose of the Study:

  • To establish the normal range of bleeding time.
  • To assess interobserver reproducibility and biological variability of the BT test.
  • To evaluate the clinical utility of BT for predicting platelet responsiveness.

Main Methods:

  • A study was conducted on 27 healthy volunteers.
  • Bleeding times were measured, with attention to reproducibility and variability.
  • Statistical analysis included calculating standard deviations and coefficients of variation.

Main Results:

  • Normal bleeding times ranged widely from 129 to 803 seconds.
  • Interobserver variability was 106 seconds (CV 18%).
  • Intra-individual variability over 6 weeks was 150 seconds (CV 27%), largely attributed to observer differences.

Conclusions:

  • Bleeding time exhibits significant inter-individual variation but low intra-individual biological variability.
  • Most observed temporal variations in bleeding time are attributable to interobserver variability.
  • Changes in an individual's bleeding time are clinically valuable for assessing platelet function over time.