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Updated: Aug 19, 2026

Coupled Assays for Monitoring Protein Refolding in Saccharomyces cerevisiae
Published on: July 9, 2013
Protein folding: versatility of the cytosolic chaperonin TRiC/CCT
1Department of Cellular Biochemistry, Max-Planck-Institut für Biochemie, Martinsried, D-82152, Germany.
Abstract:
Efficient de novo folding of actins and tubulins requires two molecular chaperones, the chaperonin TRiC (or CCT) and its novel cofactor GimC (or prefoldin). Recent studies indicate that TRiC is exquisitely adapted for this task, yet has the ability to interact with and assist the folding of numerous other cellular proteins.
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