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Gamma(delta) T cells: non-classical ligands for non-classical cells
C R Steele1, D E Oppenheim, A C Hayday
1Department of Immunobiology, GKT School of Medicine, Guy's Hospital, London, SE1 9RT, UK.
Current Biology : CB
|February 7, 2001
Abstract:
A recent study describes direct binding between a gammadelta T-cell receptor and its ligand, T22, a non-classical class I major histocompatibility complex (MHC) molecule. A companion study, solving the crystal structure of T22, highlights the differences between this interaction and those of classical MHC molecules and alphabeta T cells.