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Saccharomyces cerevisiae Models of Alzheimer's Disease to Screen Genes, Mutations, and Chemicals Affecting Amyloid Beta Production by γ-Secretase
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The pathogenic L392V mutation of presenilin 1 decreases the affinity to glycogen synthase kinase-3 beta

R Gantier1, D Gilbert, C Dumanchin

  • 1INSERM EPI 9906, Faculté mixte de Médecine et de Pharmacie, 76183 Rouen Cedex, IFRMP, 76821 Mont Saint-Aignan, Cedex, France.

Neuroscience Letters
|April 8, 2000
PubMed

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