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Updated: Oct 17, 2026

Modeling Cataract Surgery in Mice
Published on: December 1, 2023
Long-term disorders of the blood-aqueous barrier after small-incision cataract surgery
J Schauersberger1, A Kruger, A Müllner-Eidenböck
1Department of Ophthalmology, University Hospital of Vienna, Austria. joerg.schauersberger@akh-wien.ac.at
Purpose:
To determine the long-term function of the blood-aqueous barrier after small-incision cataract surgery with implantation of a foldable intraocular lens.
Methods:
The blood-aqueous barrier function in 74 eyes of 62 patients who underwent cataract surgery was examined using a laser flare-cell meter. The measurements were performed pre-operatively and post-operatively between 12 and 35 months after surgery. For statistical analysis a linear regression was used. The study was designed as a single cohort study, with comparison of pre- and post-operative values.
Results:
Highly statistically significant differences (p < 0.0001) were found between pre-operative flare values and those measured at the final visit. The linear regression model showed significantly higher flare values post-operatively compared with those measured pre-operatively. Other variables such as incision technique, sex, operation time, phaco time and systemic disease had no influence on this outcome.
Conclusion:
The results suggest that there is persistent blood-aqueous barrier dysregulation even several years after cataract surgery.
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