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Related Experiment Videos

Findings emerging from complete microbial genome sequences.

R A Clayton1, O White, C M Fraser

  • 1The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA. rclayton@tigr.org

Current Opinion in Microbiology
|February 7, 2001
PubMed
Summary
This summary is machine-generated.

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The rapid expansion of microbial genome sequencing, with 16 genomes published and over 50 more anticipated, is transforming scientific research and data sharing. This genomic revolution is paving the way for new discoveries and interdisciplinary collaboration.

Area of Science:

  • Microbiology
  • Genomics
  • Bioinformatics

Background:

  • The field of genomics has seen a significant increase in the number of completed microbial genome sequences.
  • Sixteen microorganisms, including eukaryotes, archaea, and eubacteria, have been fully sequenced.
  • Over 50 additional genomes are projected for completion by the year 2000.

Purpose of the Study:

  • To highlight the impact of the growing volume of genomic data.
  • To discuss the emergence of new scientific fields and the evolution of data sharing practices.
  • To anticipate future developments in comparative genomics.

Main Methods:

  • Analysis of published microbial genome sequencing data.
  • Projection of future genome sequencing completion rates.

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  • Assessment of the impact on scientific disciplines and information sharing.

    • Main Results:

    • A substantial increase in publicly available microbial genome sequences.
    • The establishment of foundational infrastructure for large-scale genomic projects.
    • Identification of emerging trends in bioinformatics and molecular genetics.

    Conclusions:

    • The rapid growth in genome sequencing is a transformative force in science.
    • New fields and methodologies are emerging due to this data explosion.
    • The infrastructure for global genome sequence comparisons is under development, promising future advancements.