[Antibiotic prophylaxis in cesarean section].

Area of Science:

• Obstetrics and Gynecology
• Infectious Disease Prevention

Background:

• Pelvic infections are a significant complication after cesarean sections.
• Effective prevention strategies are crucial for improving maternal outcomes.

Purpose of the Study:

• To evaluate the effectiveness of prophylactic antibiotics in preventing pelvic infections post-cesarean section.
• To quantify the reduction in infection rates attributable to antibiotic prophylaxis.

Main Methods:

• A randomized, prospective study involving 657 women undergoing cesarean section.
• Comparison of infection rates between a group receiving single-dose prophylactic antibiotics (182 women) and a control group (170 women).
• Exclusion of 305 women who received postoperative antibiotic therapy from the primary analysis.

Main Results:

• The incidence of postoperative pelvic infection was 15.93% (29 women) in the antibiotic prophylaxis group (Group B).
• The incidence of postoperative pelvic infection was 32.35% (55 women) in the control group (Group A).
• Antibiotic prophylaxis reduced the frequency of pelvic infections by 2.03 times.

Conclusions:

• Prophylactic antibiotic administration is an effective method for preventing pelvic infections after cesarean section.
• Implementing antibiotic prophylaxis can significantly decrease the risk of postoperative pelvic infections.