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[Hypersensitivity reactions to antilipemic drugs]
G Palel1, E A Coman, G Siniţchi
1Disciplina Medicină internă de ambulator-alergologie, Universitatea de Medicină şi Farmacie Gr. T. Popa, Iaşi.
Abstract:
Chronic utilization of hipolipemiants drugs makes possible the onset of hypersensitivity reactions like a part of secondary reactions. From the point of our experience the most frequent hyperreactivity appears on fibric acid derivates. Al the cases we treated, were skin manifestations (angioedema) and about 29%, were digestive manifestations (dyspepsia, vomiting, diarrhoea). At the same time, chronic utilization of nicotinic acid derivates favored skin rash due to congestive intrinsic effect of nicotinic acid.