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[Nosocomial staphylococcal meningitis]

D Mihalache1, V Luca, I Teodorescu

  • 1Clinica de Boli Infecţioase, Facultatea de Medicină, Universitatea de Medicină şi Farmacie Gr. T. Popa, Iaşi.

Revista Medico-Chirurgicala a Societatii De Medici Si Naturalisti Din Iasi
|April 11, 2000
PubMed
Abstract

Insights

Iatrogenic staphylococcal meningitis, often following neurosurgery, presents with mild symptoms. The most effective treatment involves combining cefotaxime with an aminoglycoside, with vancomycin reserved for resistant cases.

Area of Science:

  • Infectious Diseases
  • Neurology
  • Bacteriology

Context:

  • Iatrogenic staphylococcal meningitis is a serious complication following neurosurgical interventions.
  • This study analyzes 33 cases over a 10-year period (1988-1997).
  • Predisposing factors include neurosurgical procedures, chronic otomastoiditis, and shunts.

Purpose:

  • To conduct a clinical, bacteriological, and therapeutic study of iatrogenic staphylococcal meningitis.
  • To identify predisposing factors and clinical presentation.
  • To evaluate treatment efficacy and outcomes.

Summary:

  • Retrospective analysis of 33 iatrogenic staphylococcal meningitis cases.
  • Staphylococcus aureus and Staphylococcus epidermidis were the primary pathogens, generally sensitive to antibiotics.
  • Cefotaxime combined with gentamicin demonstrated the highest efficacy, with vancomycin used in only two cases.

Impact:

  • Highlights the importance of early diagnosis and appropriate antibiotic therapy.
  • Suggests cefotaxime and aminoglycoside combination as a preferred treatment regimen.
  • Provides insights into managing this specific type of meningitis in clinical practice.

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