Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Stem cell therapy and gene transfer for regeneration.

T Asahara1, C Kalka, J M Isner

  • 1St Elizabeth's Medical Center, Tufts University School of Medicine, Boston, MA, USA.

Gene Therapy
|April 11, 2000
PubMed
Summary

Adult stem cells offer practical advantages over embryonic stem cells for tissue regeneration. Gene therapy applications focus on enhancing stem cell potency, organ properties, and regeneration speed.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

New recommendations on cerebral venous and dural sinus thrombosis from the German consensus-based (S2k) guideline.

Neurological research and practice·2024
Same author

Diagnostics and Therapy of Venous Thrombosis and Pulmonary Embolism. The revised AWMF S2k Guideline

VASA. Zeitschrift fur Gefasskrankheiten·2023
Same author

Venous Leak Embolization in Patients with Venogenic Erectile Dysfunction via Deep Dorsal Penile Vein Access: Safety and Early Efficacy.

Cardiovascular and interventional radiology·2023
Same author

Hamostaseologie·2019
Same author

Persistently increased expression of the transforming growth factor-β1 gene in human vascular restenosis: Analysis of 62 patients with one or more episode of restenosis.

Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology·2015
Same author

Evaluation of angiogenesis.

Methods in molecular medicine·2011

Area of Science:

  • Regenerative Medicine
  • Gene Therapy
  • Stem Cell Biology

Background:

  • Adult stem and progenitor cells are isolated from various tissues.
  • These cells include hematopoietic, neural, mesenchymal, and endothelial progenitor cells.
  • Adult stem cells present advantages over embryonic stem cells for therapeutic applications.

Purpose of the Study:

  • To review the gene therapy applications of adult stem and progenitor cells.
  • To discuss modifications in stem cell potency.
  • To explore alterations in organ properties and regeneration acceleration.

Main Methods:

  • Literature review of gene therapy applications in adult stem cells.
  • Analysis of studies on stem cell potency modification.
  • Examination of research on organ regeneration and expressional organization.

Main Results:

  • Adult stem cells show significant potential for tissue regeneration.
  • Gene therapy can enhance stem cell potency and accelerate regeneration.
  • Applications include altering organ properties and forming expressional organization.

Conclusions:

  • Gene therapy holds promise for advancing the therapeutic use of adult stem cells.
  • Modifying stem cell potency and accelerating regeneration are key applications.
  • Further research can optimize these strategies for tissue regeneration.

Related Experiment Videos