Relative sparing of emotionally influenced memory in Alzheimer's disease

Studies suggest that emotionally influenced events enhance long-term memory. This study aimed to uncover whether this phenomenon exists in Alzheimer's Disease (AD) by comparing patients' performance with that of controls on a memory task. Overall, controls performed better than AD subjects on a delayed recognition task of a story containing emotional elements (95.8+/-2.4% vs 66.6+/-28.5%; mean +/- s.d.), respectively. Among AD subjects, there was relative sparing of emotionally influenced memory, which was not seen in controls because of a ceiling effect. Retention of the emotional phase of the story differed significantly from that of the neutral phases. These findings suggest that the influence of emotion on memory is spared, at least to some degree, in AD.