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Updated: Oct 17, 2026

Dosimetry for Cell Irradiation using Orthovoltage (40-300 kV) X-Ray Facilities
Published on: February 20, 2021
On the beam quality specification of high-energy photons for radiotherapy dosimetry
1Dosimetry and Medical Radiation Physis Section, International Atomic Energy Agency, Vienna, Austria. p.andreo@iaea.org
Abstract:
An overview of common photon beam quality specifiers used in radiotherapy dosimetry introduces a reasoned discussion on the advantages and disadvantages of TPR20,10 and PDD(10)x. It is shown that some of the potential advantages of PDD(10)x are also present in other well known beam quality specifiers such as d80. However, all PDD-based beam quality indices, including PDD(10)x, are subject to electron contamination and their determination is affected by practical limitations. The proposed filtration of contaminant electrons by Kosunen and Rogers [Med. Phys. 20, 1181-1188 (1993)] and by Li and Rogers [Med. Phys. 21, 791-798 (1994)] is questioned, not only with regard to the adequacy of using lead as an electron filter, but also in relation to its efficiency (if there were no contamination, restrictions for beam calibrations at dmax would be removed) and practical measurement. It is argued that (i) there is no unique beam quality specifier that works satisfactorily in all possible conditions, for the entire energy range of photon energies used in radiotherapy and all possible accelerators used in hospitals and in standards laboratories, and (ii) TPR20,10 remains to be the most appropriate specifier for clinical photon beams as it has less practical drawbacks than PDD-based quality indices. The final impact on clinical photon beam dosimetry resulting from the use of different photon beam quality specifiers, is that they are not expected to yield a significant change (i.e., more than 0.5% and in most cases well within 0.2%) in the absorbed dose to water in reference conditions for most clinical beams.
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