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Published on: August 7, 2017
Parental history of migraine and bronchial asthma in children
1Dicle Univ, Cocuk Servisi, Diyarbakir, Turquía. fuatgurkan@hotmail. com
Insights
Children with a parental history of migraine have a significantly higher risk of developing asthma. This suggests a potential genetic link between migraine and childhood asthma.
Area of Science:
- Pediatrics
- Genetics
- Allergology
Background:
- Migraine is potentially associated with allergic disorders.
- The relationship between parental migraine history and childhood asthma requires further investigation.
Purpose of the Study:
- To examine the association between bronchial asthma in children and a parental history of migraine.
Main Methods:
- A case-control study was conducted with 140 asthmatic children and 110 control subjects.
- Parental history of allergic diseases and migraine was collected via inquiry.
Main Results:
- Asthmatic children had a significantly higher prevalence of parental migraine history (9.3%) compared to controls (1.8%).
- Parental migraine history was associated with increased parental asthma, eczema, and allergic rhinitis.
Conclusions:
- Children with a parental history of migraine are at increased risk for asthma.
- The findings suggest a potential common underlying factor linking migraine and asthma across generations.
Background:
a possible association between migraine and various allergic disorders have been reported. It was aimed in this study to inquire the association between bronchial asthma in children and parental history of migraine.
Methods And Results:
parental history of allergic diseases and migraine were inquired among 140 asthmatic children (91 males, 49 females) and 110 age and sex matched control subjects who had not any allergic or hypersensitivity disorders, followed-up at Pediatric outpatient clinics of Dicle University Hospital. While 13 of 140 asthmatic children (9.3%) had parental history of migraine, 2 of 110 control subjects (1.8%) had parental migraine history. Difference between asthmatic and control subjects was significant (OR: 5.5, 95% Cl: 1.3-25.0). Children who had parental history of migraine also had significantly more frequent parental history of asthma, eczema and particularly allergic rhinitis (p=0.007).
Conclusions:
our results suggest that children are at increased risk of asthma if their parents have a history of migraine. Migraine in one generation and asthma in the next lead to the conclusion that the two disorders may have a relationship to a common denominator.
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