Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Update on hereditary optic neuropathy.

M T Yen1, B L Lam

  • 1Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, FL, USA.

Seminars in Ophthalmology
|April 12, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ophthalmic presentation of giant cell arteritis in African-Americans.

Eye (London, England)·2016
Same author

Automated Quantitation of Spinal CSF Volume and Measurement of Craniospinal CSF Redistribution following Lumbar Withdrawal in Idiopathic Intracranial Hypertension.

AJNR. American journal of neuroradiology·2016
Same author

Automated quantitation of the posterior scleral flattening and optic nerve protrusion by MRI in idiopathic intracranial hypertension.

AJNR. American journal of neuroradiology·2013
Same author

MRI evidence of impaired CSF homeostasis in obesity-associated idiopathic intracranial hypertension.

AJNR. American journal of neuroradiology·2012
Same author

Predicting the pathogenicity of RPE65 mutations.

Human mutation·2009
Same author

Genetic heterogeneity in autosomal dominant retinitis pigmentosa with low-frequency damped electroretinographic wavelets.

Eye (London, England)·2008
Same journal

Longitudinal Structural and Functional Trajectories Following Netarsudil Intensification or Surgical Escalation in Primary Open-Angle Glaucoma.

Seminars in ophthalmology·2026
Same journal

Maternal Diabetes Mellitus During Pregnancy as a Risk Factor for Congenital Nasolacrimal Duct Obstruction in the Offspring - a Large-Scale National Study.

Seminars in ophthalmology·2026
Same journal

Clinical Spectrum and Genetics of Ocular Manifestations in Muscle Eye Brain Disease: A Literature Review.

Seminars in ophthalmology·2026
Same journal

Port Delivery System Vs Monthly Ranibizumab in VEGF-Driven Macular Disease: A Systematic Review and Meta-Analysis.

Seminars in ophthalmology·2026
Same journal

Genome Wide Pleiotropic Analysis Reveals Shared Genetic Architecture and Pathological Basis Between Retinitis Pigmentosa and Relevant Ocular Comorbidities.

Seminars in ophthalmology·2026
Same journal

Does QuantiFERON-Positive Tubercular Serpiginous-Like Choroiditis Affect Retinal and Choroidal Structures Differently in Affected Eyes Compared to Fellow Eyes and Healthy Controls? A Comparative OCT and OCT-A Study.

Seminars in ophthalmology·2026
See all related articles

Genetic research is improving the evaluation and management of hereditary optic neuropathies, even without available treatments. This review covers key genetic information for Leber's hereditary optic neuropathy, dominant optic atrophy, recessive optic atrophy, and Wolfram syndrome.

Area of Science:

  • Ophthalmology
  • Genetics
  • Neurology

Background:

  • Hereditary optic neuropathies (HONs) are a group of genetic disorders affecting vision.
  • Currently, no specific treatments exist for most HONs.
  • Recent advances in genetic identification offer new avenues for patient management.

Purpose of the Study:

  • To review the clinical features and genetic information of specific hereditary optic neuropathies.
  • To highlight the impact of genetic discoveries on patient evaluation and care.

Main Methods:

  • Literature review of hereditary optic neuropathies.
  • Synthesis of clinical and genetic data for selected conditions.

Main Results:

  • Identified genetic loci for several HONs, aiding diagnosis.

Related Experiment Videos

  • Detailed clinical presentations of Leber's hereditary optic neuropathy, dominant optic atrophy, recessive optic atrophy, and Wolfram syndrome.

    • Conclusions:

    • Genetic insights are crucial for understanding and managing HONs.
    • Further research into genetic causes may lead to future therapeutic strategies.