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Obsessive-compulsive disorder in schizophrenia.

P Tibbo1, M Kroetsch, P Chue

  • 1Department of Psychiatry, University of Alberta Hospital, 1E7.36 WMC, Edmonton, Canada. ptibbo@pop.srv.ualberta.ca

Journal of Psychiatric Research
|April 12, 2000
PubMed
Summary
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Schizophrenia patients with comorbid obsessive-compulsive disorder (OCD) showed distinct clinical features. These patients had less negative symptoms and more Parkinsonian symptoms compared to those with schizophrenia alone.

Area of Science:

  • Psychiatry
  • Clinical Psychology

Background:

  • Schizophrenia is a severe mental disorder.
  • Obsessive-compulsive disorder (OCD) is a distinct psychiatric condition.
  • Comorbidity between schizophrenia and OCD presents unique clinical challenges.

Purpose of the Study:

  • To investigate demographic and clinical differences in schizophrenia patients with and without comorbid OCD.
  • To identify specific symptom profiles associated with schizophrenia and OCD comorbidity.

Main Methods:

  • Recruited 52 subjects from clinical services in Edmonton, Alberta.
  • Utilized structured clinical interviews and standardized rating scales to assess for schizophrenia and OCD.
  • Employed scales such as Y-BOCS, Hollingshead scale, GAF, and PANSS.

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Main Results:

  • The prevalence of OCD in schizophrenia patients was 25%.
  • Patients with comorbid schizophrenia and OCD had higher scores on Y-BOCS, Hollingshead scale, and GAF.
  • These patients also exhibited significantly lower PANSS negative symptoms and a trend towards increased Parkinsonian symptoms.

Conclusions:

  • Patients with schizophrenia and comorbid OCD differ in demographic and clinical measures from those with schizophrenia alone.
  • Reduced negative symptoms in comorbid patients may correlate with decreased GAF scores.
  • Increased Parkinsonian symptoms in comorbid patients suggest potential basal ganglia dysfunction.