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Chemotherapy for Advanced Gastric Cancer: Focus on New Agents and Combinations
1Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Cancer Control : Journal of the Moffitt Cancer Center
|April 12, 2000
Abstract:
BACKGROUND: Although many treatments for advanced gastric cancer have been developed, systemic therapy remains elusive. METHODS: The author reviewed data on recent phase II and III trials of the main new agents and combinations. RESULTS: Chemotherapy appears to improve survival of patients with advanced disease, albeit slightly. New drugs that might improve response rates and survival include the taxanes. CONCLUSIONS: New combinations, including the taxanes, must be designed and evaluated to further improve the outcome for patients with advanced gastric cancer.