[Acute renal insufficiency in children]

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Updated: Oct 17, 2026

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
09:02

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion

Published on: February 2, 2021

D Milicić1, E Cemerlić-Zecević, V Misanović

  • 1Pedijatrijska klinika, Klinicki centar Univerziteta u Sarajevu.

Medicinski Arhiv
|April 12, 2000
PubMed

Insights

Acute renal failure (ARF) in children is often temporary and requires prompt diagnosis and treatment for recovery. Early intervention and prevention are key to reducing mortality in pediatric ARF cases.

Area of Science:

  • Pediatric Nephrology
  • Critical Care Medicine

Context:

  • Acute renal failure (ARF) is a significant concern in hospitalized children, particularly neonates and infants.
  • Sudden glomerular and tubular dysfunction necessitates rapid diagnosis and intervention to ensure kidney function recovery and minimize mortality.

Purpose:

  • To describe the common causes, diagnostic procedures, and non-dialytic treatments for ARF in pediatric patients.
  • To evaluate the outcomes of conservative management in a cohort of children with ARF.

Summary:

  • This study analyzed 51 pediatric patients (newborn to 16 years) with ARF, categorizing causes into prerenal, renal, and postrenal.
  • Diagnosis involved history, physical examination, laboratory tests, and radiology. Conservative treatment was successful in 45 patients; 6 deaths occurred due to underlying conditions.

Impact:

  • Highlights the critical importance of prevention, early diagnosis, and timely therapy for conditions leading to pediatric ARF.
  • Emphasizes that a multidisciplinary approach is essential for the successful management of acute renal failure in children.

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