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Updated: Aug 27, 2026
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Left Lung Orthotopic Transplantation in a Juvenile Porcine Model for ESLP
Published on: February 14, 2022
A porcine ex vivo paracorporeal model of lung transplantation
N C Wright1, D N Hopkinson, T E Shaw
1Biological Services Unit, The Medical School, University of Manchester, UK.
Laboratory Animals
|April 12, 2000
Abstract:
A technique is described which allows perfusion of an isolated, ventilated pig lung with an extracorporeal veno-venous circuit from a support animal. This model is stable for up to 4 h, and avoids some of the disadvantages of alternative small animal and large animal models of lung transplantation. It may be useful in the investigation of factors affecting lung preservation and reperfusion injury.
