Related Experiment Videos
Comparative palatability of 22 liquid antacids
1College of Pharmacy, The Ohio State University, Columbus, USA. temple.9@osu.edu
Alimentary Pharmacology & Therapeutics
|April 12, 2000
Summary
Mylanta Lemon Twist and Cherry Crème offered the best taste among tested antacids, though overall palatability was poor. Extra strength antacids provided superior acid neutralization, making them a cost-effective choice despite higher initial price.
Area of Science:
- Gastroenterology
- Pharmacology
Background:
- Antacids are widely used for symptomatic relief of acid-related gastrointestinal disorders.
- Patient preference and efficacy are key factors in antacid selection.
Purpose of the Study:
- To evaluate and compare the palatability, acid-neutralizing capacity, and cost-effectiveness of various over-the-counter antacids.
Main Methods:
- A sensory evaluation of 22 antacids was conducted by 73 adult volunteers (ages 18-60).
- Participants rated antacids on smell, taste, texture, and aftertaste using a 1-9 scale.
- Acid-neutralizing capability and cost per milliequivalent (mEq) were analyzed.
Main Results:
- Mylanta Lemon Twist and Mylanta Cherry Crème were the most palatable, though overall palatability was generally poor.
- Extra strength antacids demonstrated the highest acid-neutralizing capability.
- Amphogel was the most expensive antacid on a cost-per-mEq basis.
Conclusions:
- While Mylanta variants were most palatable, extra strength formulations offer superior acid neutralization and cost-efficiency.
- Extra strength antacids may be preferred due to their enhanced efficacy and reduced dosage requirements.