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Related Experiment Video

Updated: Jul 12, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

The migraine ACE model: evaluating the impact on time lost and medical resource Use.

J J Caro¹, G Caro, D Getsios

¹Caro Research, Boston, Mass; Caro Research, Montreal, Quebec, Canada.

|April 12, 2000

Summary

This summary is machine-generated.

Migraine significantly impacts daily life and incurs substantial costs due to lost productivity and medical expenses. The Migraine Adaptive Cost-Effectiveness Model helps evaluate treatments for this condition.

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Area of Science:

Health Economics
Pharmacoeconomics
Epidemiology

Background:

Migraine is prevalent, causing significant societal economic burden and impacting patient functioning.
Improved pharmaceutical treatments necessitate economic impact assessments.
A novel model was developed to evaluate the economic implications of migraine treatments.

Purpose of the Study:

To describe the Migraine Adaptive Cost-Effectiveness Model.
To analyze the economic impact of migraine in a simulated Canadian patient population.

Main Methods:

The Migraine Adaptive Cost-Effectiveness Model was developed.
It incorporates costs of lost work/nonwork time, medical resources, and medications.
Monte Carlo simulation was used to model a patient population over one year.

Main Results:

Customary therapy resulted in an estimated $1949 per patient in productivity losses (84 hours paid work, 48 hours unpaid work, 113 hours leisure).
Medical expenditures added an average of $280 per patient.
Total estimated cost of illness per patient was $2229.

Conclusions:

Migraine imposes substantial costs due to reduced functional capacity with current treatments.
The developed model is a flexible tool for economic evaluations of various migraine treatments.
The model can be applied to diverse patient populations for cost-effectiveness analysis.