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Hepatitis C virus (HCV) NS5A protein: role in HCV replication and resistance to interferon-alpha
1Department of Bacteriology and Virology and INSERM U99, Hôpital Henri Mondor, Université Paris XII, Créteil, France.
Journal of Viral Hepatitis
|April 12, 2000
Abstract:
The hepatitis C virus (HCV) non-structural (NS) 5A protein appears to play an important regulatory role on viral replication and could also be involved in viral pathogenesis. HCV resistance to interferon is a complex mechanism involving multiple causes, among which certain NS5A functions could play a role.