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Right temporal lobe glioblastoma presenting in the left orbit. Case report.
J M Kros1, H van den Berge, H L Tanghe
1Department of Pathology, University Hospital Rotterdam, The Netherlands.
Journal of Neurosurgery
|April 13, 2000
Summary
Glioblastoma multiforme (GBM) rarely spreads outside the central nervous system, especially to bone or the orbit without prior surgery. This case highlights GBM
Area of Science:
- Neuro-oncology
- Pathology
Background:
- Gliomas rarely disseminate outside the central nervous system (CNS).
- Primary glial neoplasms presenting as bone lesions are exceptionally rare.
Observation:
- A glioblastoma multiforme (GBM) case presented initially in the orbit after a seizure.
- Intracranial hypertension was caused by subarachnoid tumor spread.
Findings:
- The patient received radiation therapy but survived only 6 months.
- Autopsy confirmed right temporal GBM with extensive subarachnoid spread and invasion into the orbit and skull base.
Implications:
- This case underscores the potential for rare patterns of CNS tumor dissemination.
- Understanding these rare presentations is crucial for diagnosis and management.