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Smoking and the molecular epidemiology of lung cancer
1Department of Occupational Medicine and Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA. dchris@hohp.harvard.edu
Clinics in Chest Medicine
|April 14, 2000
Abstract:
Lung carcinogenesis in humans requires exposure to environmental agents, including the inhalation of tobacco smoke, radioactive compounds, asbestos, heavy metals, and petrochemicals. Tobacco smoking is the risk factor with the highest attributable lung cancer risk worldwide. This article discusses occupational carcinogen exposure and exposure from tobacco use, and the lung-cancer risk associated with these types of exposure.