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[Olfactory esthesioneuroma manifesting as Schwartz-Bartter syndrome]
P Bernard1, D Vitrey, C Boursier
1Département de la clinique médicale, hôpital d'instruction des armées Desgenettes, Lyon, France.
La Revue De Medecine Interne
|April 14, 2000
Abstract
Introduction:
Olfactory esthesioneuroblastoma is an uncommon neuroectodermal tumor originating from the olfactory epithelium, which is rarely associated with hormone excess syndrome.
Exegesis:
Asymptomatic olfactory esthesioneuroblastoma was diagnosed in a 22-year-old man who presented a syndrome of inappropriate antidiuretic hormone secretion. Following surgery, the immunohistochemical analysis demonstrated the existence of neurophysin hormone in tumoral cells.
Conclusion:
This case provides evidence that olfactory esthesioneuroblastoma can be uncovered by inappropriate antidiuretic hormone secretion.