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Effects of alkaline hydrolysis and dynamic coating on the electroosmotic flow in polymeric microfabricated channels
S C Wang1, C E Perso, M D Morris
1Department of Chemistry, University of Michigan, Ann Arbor 48109-1055, USA.
Analytical Chemistry
|April 14, 2000
Abstract:
Protocols are described for control of the electroosmotic flow in microfabricated channels in Vivak copolyester. Alkaline hydrolysis of surface ionizable groups alone or such hydrolysis in combination with dynamic coating with cetyltrimethylammonium bromide (CTAB) is shown to provide reproducible electroosmotic flows. Dynamic coating with CTAB can be used to eliminate electroosmosis or to reverse its direction, depending on the concentration employed.