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Updated: Oct 17, 2026

A Murine Model of Group B Streptococcus Vaginal Colonization
Published on: November 16, 2016
Chemoprophylaxis of early-onset group B streptococcal disease in 1999
1Department of Pediatrics, Rush-Presbyterian St. Luke's Medical Center, Chicago, Illinois 60612-3833, USA.
Abstract:
The evolution of the guidelines for selective intrapartum chemoprophylaxis (SIC) of group B streptococcal early-onset disease is reviewed here. To assess the benefits of the risk-based and culture-based strategies for prevention, observational studies since 1996 are summarized. The effect of chorioamnionitis on group B streptococcal early-onset disease, despite SIC, is emphasized. Optimal management remains controversial, and alternative strategies for the selection of women for chemoprophylaxis and for the management of infants are discussed.
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