Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Age and the Risk of Breast Cancer Recurrence.

Lyman1, Lyman, Balducci

  • 1Department of Internal Medicine, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612, USA.

Cancer Control : Journal of the Moffitt Cancer Center
|October 1, 1996
PubMed
Summary

Elderly women with breast cancer often have better prognostic factors and outcomes than younger patients. Age should not be a factor in determining breast cancer prognosis or treatment.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pulmonary embolism.

The Broadway·2010
Same author

The Potential of SERMs for Reducing the Risk of Coronary Heart Disease.

Trends in endocrinology and metabolism: TEM·2001
Same author

DNA vaccines for cancer therapy.

Expert opinion on investigational drugs·2001
Same author

Concepts in Ras-directed therapy.

Expert opinion on investigational drugs·2001
Same author

Letters to the Editor.

Journal of hand surgery (Edinburgh, Scotland)·2000
Same author

Reducing seat dip attenuation

The Journal of the Acoustical Society of America·2000

Area of Science:

  • Oncology
  • Geriatric Medicine
  • Epidemiology

Background:

  • Prognostic factors are crucial for breast cancer management.
  • Evaluating these factors in elderly populations is essential for tailored treatment.
  • This study focuses on breast cancer outcomes in women aged 65 and older.

Purpose of the Study:

  • To assess the impact of prognostic factors on breast cancer outcomes in elderly women.
  • To compare disease outcomes and survival rates between elderly and younger breast cancer patients.
  • To determine if advanced age is a negative prognostic indicator for breast cancer.

Main Methods:

  • Retrospective cohort analysis of 1,267 locoregional breast cancer patients.
  • Inclusion of 374 patients aged 65 years or older.

Related Experiment Videos

  • Analysis of prognostic factors, disease recurrence, and overall survival.

    • Main Results:

    • Elderly women (≥65 years) more frequently presented with early-stage cancers.
    • Older patients exhibited favorable prognostic markers: lower histologic grade, higher hormone receptor levels, and lower S-phase fractions.
    • Women aged 65 and older demonstrated longer disease-free survival and overall survival compared to younger counterparts.

    Conclusions:

    • Advanced age is not an unfavorable prognostic factor for breast cancer.
    • Breast cancer prognosis and treatment decisions should prioritize disease stage and biological parameters over patient age.
    • Personalized treatment strategies based on individual tumor characteristics are recommended for all age groups.