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Updated: Aug 18, 2026

Subretinal Transplantation of MACS Purified Photoreceptor Precursor Cells into the Adult Mouse Retina
Published on: February 22, 2014
Improvement in macular function after retinal translocation surgery in a patient with age-related macular
M J Potter1, T S Chang, A S Lee
1Department of Ophthalmology, University of British Columbia, Vancouver, BC, Canada. mpotter@interchange.ubc.ca
Purpose:
To assess focal electroretinographic findings before and after retinal translocation surgery in a patient with age-related macular degeneration.
Method:
Case report. A 79-year-old man with a well-defined subfoveal choroidal neovascular membrane from age-related macular degeneration underwent preoperative and postoperative focal electroretinography.
Results:
After retinal translocation surgery, best-corrected Snellen visual acuity improved from 9/200 to 20/60. A significant increase in mean foveal amplitude, from 0.08 microV to 0.16 microV (P = 0.008) was recorded.
Conclusion:
Age-related macular degenerative changes in visual acuity and foveal electroretinogram amplitude may be reversible after retinal translocation surgery.

