Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Measures to reduce infarct size (author's transl)].

H Zilcher

    Wiener Klinische Wochenschrift
    |January 19, 1979
    PubMed
    Summary

    Reducing infarct size in acute myocardial infarction is challenging due to delayed hospital admission. Optimizing hemodynamics and enhancing collateral circulation may benefit patients, but prognosis depends on underlying coronary heart disease.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Ketanserin combined with a beta-blocker or diuretic in essential hypertension. A multicentre study.

    European journal of clinical pharmacology·1988
    Same author

    [Problems in the care of hypertensive patients].

    Wiener medizinische Wochenschrift (1946)·1984
    Same author

    [Indications for heart valve surgery from a cardiological viewpoint].

    Wiener medizinische Wochenschrift (1946)·1984
    Same author

    [Modern aspects of cardiogenic shock].

    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete·1983
    Same author

    [Arrhythmias and their treatment].

    ZFA. Zeitschrift fur Allgemeinmedizin·1982
    Same author

    [Graduated plan for the treatment of hypertension].

    Medizinische Klinik·1981

    Area of Science:

    • Cardiology
    • Cardiovascular Surgery

    Context:

    • Acute myocardial infarction (AMI) management is often delayed, limiting therapeutic windows.
    • The critical period for salvaging ischemic myocardium is typically within 6-8 hours post-infarction.
    • Many patients present after this window, complicating infarct size reduction strategies.

    Purpose:

    • To explore therapeutic strategies for managing acute myocardial infarction (AMI) when patients present late.
    • To discuss the role of hemodynamic optimization and collateral circulation enhancement in salvaging ischemic myocardium.
    • To evaluate the limitations of current interventions, including cardiac surgery and intra-aortic balloon pumping.

    Summary:

    • Infarct size reduction is clinically limited by delayed hospital admission post-myocardial infarction.
    • Hemodynamic management (preload, afterload manipulation) and enhanced collateral circulation can benefit patients with compromised myocardial oxygen balance.
    • Late reperfusion and limitations of interventions like intra-aortic balloon pumping pose challenges.

    Impact:

    • Current strategies have improved hospitalization but do not alter long-term prognosis.
    • Prognosis in acute myocardial infarction remains primarily determined by the extent of underlying coronary heart disease.
    • Further research is needed to improve outcomes for patients presenting beyond the critical therapeutic window.

    Related Experiment Videos