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Myoblast therapy for stress urinary incontinence and bladder dysfunction
T Yokoyama1, J Huard, M B Chancellor
1Division of Urologic Surgery, University of Pittsburgh School of Medicine, Pennsylvania, USA.
Abstract:
The field of tissue engineering and gene therapy has an exciting and promising future. During the past few years we have begun a comprehensive effort to investigate the use of myoblasts to improve and expand the treatment of stress urinary incontinence and bladder dysfunction. Moreover, we can expect the application of myoblast-mediated ex vivo gene transfer in the field of urology. In this paper we discuss the compositions of and methods involving the use of myogenic or muscle-derived cells for tissue engineering and cell-mediated gene therapy.
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